HIV is a retrovirus that integrates into CD4 T lymphocytes (a critical component of cell-mediated immunity), causing cell death and resulting in severe immunodeficiency, opportunistic infections (OI), and malignancies
Tagged: hiv transmission
Chancroid is a sexually transmitted disease characterized by painful genital ulcerations and inflammatory inguinal adenopathy. Although uncommon in the US, it is found worldwide. Chancroid is endemic in developing countries, especially sub-Saharan Africa, and is a co-factor for HIV transmission.