Category: Psychopharmacology

Schizophrenia – The Genain Quadruplets

A startling case history documented and compiled over a number of years by David Rosenthal and colleagues at the National Institute of Mental Health (Rosenthal, 1963) has provided fascinating insights into the interaction of...

Neurochemical Models of Schizophrenia

To identify the neurochemical basis for any mental disorder, three general approaches can be taken. First, neurochemical correlates of animal and human models of the disorder can be studied. Second, the neuronal mechanisms of...

Etiology of Schizophrenia

Scientists from several disciplines use a variety of strategies to uncover the causes of schizophrenia. The goal is to develop an integrated approach to psychopathology considering anatomical, neurochemical, and functional factors. Schizophrenia is best...

Preclinical Models of Schizophrenia

Animal models of schizophrenia are important for identifying the neurochemical and genetic basis for the disorder. They are also vital for screening new antipsychotic drugs. Developing such models is difficult, however, because the primary...