Category: Skin care

Acne Vulgaris Therapy – Topical antibiotics

INTRODUCTION Topical antibiotics have been an integral component of the topical armamenta-rium for the treatment of acne vulgaris for approximately four decades and remain commonly prescribed by dermatologists in clinical practice (1,2). Over time,...

Enhancing the success of acne vulgaris therapy

Current concepts of acne therapy date to the mid-20th century with the introduction of broad-spectrum antibiotics, notably the tetracyclines, and estrogen, in the form of oral contraceptives. This was followed by enhanced topical therapy...

Innate immunity in the pathogenesis of acne vulgaris

INTRODUCTION Acne vulgaris is a disease of pilosebaceous units. Major hypotheses on its pathophysiology include the following (1,2): Altered follicular keratinization (hyperkeratinization) of the pilosebaceous unit (3) Propionibacterium acnes (P. acnes) follicular colonization and...