Category: Neurology

Additional Agents and Miscellaneous Therapies

Sedative-Hypnotics These drugs in general, and clonazepam in particular, were among the first used and reported on (in 1979) for the treatment of restless legs syndrome (RLS).1 However, their ability to specifically alleviate RLS...

Opioid Agents in the Treatment of Restless Legs Syndrome

Opioid medications prove particularly beneficial in patients with severe restless legs syndrome (RLS) or who have developed complications, such as augmentation, on other therapy. Al-though addiction and side effects require close monitoring, it is...

Dopaminergic Therapy of Restless Legs Syndrome

Since Akpinar’s original 1982 report1 on the dramatic effects of levodopa on restless legs syndrome (RLS) symptoms, there have been numerous, independent studies that have validated these findings and that have substantially verified the...